HPV Treatment Breakthrough: AHCC

AHCC® Clears HPV Infections as Shown in New Study

Phase 2 Clinical Trial Shows AHCC® Which is Derived from Shiitake Mushrooms Effectively Clears HPV Infections

With the recent results of a Phase II AHCC® study demonstrating a 58% effective rate for clearing persistent HPV infections, this breakthrough is life changing and provides serious hope for good health.

If you have HPV, you are at risk for getting cancer, but until recently there has been no cure and there has been no systemic treatment available.  Doctors’ suggestions include nutritional and lifestyle changes for stress reduction to help strengthen the immune system. Survivors of cancers from HPV live in the fear they may come back again.

Most people clear an HPV infection within 2 years with a strong immune system.  The immune system is weakened as a result of age, stress, lack of sleep or a diet lacking in proper nutrients. An HPV infection is considered persistent if it lasts more than 2 years which occurs in approximately 10% of people with HPV.  It becomes more likely cancer cells will form the longer the HPV is active.

High risk HPV infections are the most common to cause cancer. High risk HPV individuals with compromised immune systems are in need of a supplement to build up their immunity and assist in clearing persistent HPV infections. Today’s treatments for HPV are based on early detection when a vaginal PAP smear is done.  This often leads to a cryotherapy treatment, LEEP procedure, surgical excision or cold knife conization.  Even though patients have a good result from these treatments over 80% will have lesions that are recurrent and there are no protocols for treating HPV in the rest of the body.

Although new forms of screenings are being developed they are only done in limited cities. For example there’s a study that done called the Anchor Study that showed that HPV screenings and treatments for cells that are precancerous lowers the incidence of cancer of the anus.

The best case for preventing HPV infections from turning into cancer is the development of improved nutrient dense immunity building supplement such as AHCC®.  This is the basis of the Phase II AHCC® Clinical Study and why it is of such critical importance to millions of individuals.

AHCC® Life Changing Potential

AHCC@ is a revolutionary, patented ingredient made from the standardized extract from the mycelia of Shiitake mushrooms or cultured lentinula edodes shown to include immune modulatory benefits that are completely unique.

There have been numerous human studies done from well regarded institutions reporting the benefits of AHCC® including modulation of the human immune system, preventing infections which are viral and bacterial, anticancer activity, and enhanced antioxidant effects.

The promise of AHCC® started with positive results from 2 initial pilot studies. In the first study, women with HPV infections that were persistent, 50% of the individuals cleared their infections in 3-6 months by taking AHCC® daily on an empty stomach.  (The study included 8 women taking 3g of AHCC® daily.)  In the second study, women with HPV infections that were persistent, 44% of the individuals cleared their infections in 7 months by taking AHCC® daily on an empty stomach.  (The study included 9 women taking 1g of AHCC® daily.)

The results of these pilot studies was the impetus to proceed with the phase II clinical trial of AHCC® to clear persistent infections resulting from HPV. The key finding in the new phase II clinical trial is AHCC® helps the human immune system get rid of Human Papilloma Virus Infections (HPV).

The New AHCC® Clinical Phase II Trial

The new AHCC® study was led by Dr. Judith Smith.  The study was a double-blind, randomized, and placebo-controlled with an additional study after that was unblinded.  The University of Texas Health Sciences Center Institutional Review Board reviewed and approved the study.

The goal of the Phase II trial was to prove whether AHCC® has the durability, efficacy and safety to clear high risk HPV infections if taken for 6 months as a supplement. The study was conducted for 12 months and included 50 women aged 30+ with HPV infections which were persistent (lasting two years or more).  There were two groups of patients randomized.

Group one took 3g of AHCC® once a day for 6 months (stomach was empty when taking) and placebo during the following 6 months. Group two was the placebo group. The patients from both groups were tested with DNA and RNA HPV testing every 3 months.  The sample of blood included immune markers for NK natural killer cell levels, INN – interferon‐alpha, IFNβ – interferon‐beta, IFN- interferon‐gamma, IgG1, and T‐lymphocytes.

For the women who participated in the study, 63.6% in the AHCC® arm were negative of HPV-RNA/HPV-DNA after 6 months; 64.3% had a response defined as also being negative of HPV-RNA/HPV-DNA after twelve months following supplementation ending. (The study included 41 women in the AHCC® group). For the women who were part of the placebo section of the study 10.5% were negative of HPV at the end of the 12 months of the study. (2 of 19 of the women were negative of HPV).  Twelve additional women were part of the study that was unblinded, of which 50% were negative for HPV-RNA/HPV-DNA after 6 months, with 3g of AHCC® daily.

When taking all 34 women who participated in the clinical study and took 3g of AHCC® daily the  response rate overall was 58.8% cleared persistent infections from HPV.

The AHCC® Study Conclusions

The Phase II Clinical Study of AHCC® taken at 3g daily on an empty stomach effectively supports the immune system in clearing  persistent infections from HPV with no side effects that were significant.  The recommended duration of supplementation of AHCC® requires further evaluation.

Further Research Required

More research is required to study AHCC® as the trials indicated IFNβ suppression of 20pg/mL and an increased IFN and T‐lymphocytes in the clearance of infections by the patients given supplementation with AHCC®.  The recommended duration of supplementation with AHCC® needs further study to optimize outcomes and success rates.

AHCC® The Only HPV Clearing Mushroom Compound

AHCC® is unique and the only HPV supplement that is clinically proven effective, made from medicinal mushrooms.  This has been specifically formulated by top scientists more than 40 years ago because of its medicinal qualities and maximum immunity strength, killer cell activities and benefits.  The scientists were able to reduce its weight and increase its efficacy and absorption.  The manufacturing process is patented and cannot be replicated by any other company in the world other than the Amino Up Corporation in Japan.

AHCC® is a registered trademark of the Amino Up Company

Can AHCC Cure HPV & What Dosage Should I Take?

The human papillomavirus, otherwise known as HPV, is a common virus that contributes to an estimated 630,000 new cancer cases annually worldwide (1). Cancer of the cervix represents over 80 percent of the cases caused by the virus. According to the CDC, other types of cancers have been attributed to HPV, such as 70 percent of oropharyngeal cancer, 90 percent of anal cancer, and 70 percent of vaginal and vulvar cancer (2). There are 100 different types of HPV, many of which do not cause cancer. However, researchers have identified 6 HPV types as definite human carcinogens (3).

Is there any way to help get rid of HPV infections? Read on to learn more about how HPV affects the body and why a supplement called AHCC may be able to help.

Do HPV Infections Go Away?

HPV often disappears from Pap test results within about two years, often without any treatment. While this scenario happens in the majority of cases, it does not always occur that way.

In some instances of HPV infections, the virus stays dormant and surfaces many years later. In these cases, the infections never really get resolved, and HPV ends up lingering for a long time. The body has a particularly hard time responding to the virus in people with weakened immune systems. When the infection persists, the potential for more serious complications increases, leading to the incidence of cervical cancer, genital warts, and other issues.

What’s the Most Effective Approach to Treat HPV?

Optimal immune function is essential to defend against pathogenic invaders like HPV. While there is no known cure for HPV infections, strengthening the immune system with natural substances such as AHCC has shown promising results.

AHCC is a cultured extract of various species of medicinal mushroom mycelia (roots). It has an immune-boosting effect that enables it to assist the body in eradicating the virus. This extract enhances immune function by increasing the number and activity of natural killer cells and other immune cells.

Over 30 human clinical trials looked at the effectiveness of AHCC in the treatment of many severe conditions, such as head and neck cancer, liver cancer, and HPV-positive cervical cancer. The results of these studies have been so impressive that some of the most prestigious institutions around the world have studied AHCC.

A pilot study at the University of Texas Health Science Center at Houston followed 10 HPV-positive women who took 3 grams of AHCC once daily for three months, and up to six months. At the end of the trial, 50% of the women tested negative for HPV (4). These are incredibly encouraging results considering that there is currently no cure for the condition.

What Dosage of AHCC Should I Take to Eradicate HPV?

Based on the best available scientific evidence, 3 grams of HPV cure AHCC. Daily AHCC appears to be an effective AHCC HPV dosage for the eradication of HPV. Treatment with this supplement makes the virus dormant in the body, so to achieve continuous suppression, it is important to continue taking the supplement indefinitely.
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Sources
  1. Worldwide burden of cancer attributable to HPV by site, country and HPV type: National Institutes of Health, 2017.
  2. HPV-Associated Cancer Statistics: Centers for Disease Control and Prevention, 2018.
  3. Global burden of human papillomavirus and related diseases: National Institutes of Health, 2012.
  4. Mushroom extract, AHCC, helpful in treating HPV: ScienceDaily, 2014.

Is there a permanent cure to suppress HPV?

Unfortunately, no medical cure presently exists to eliminate an HPV infection. An infected person must rely on their immune system to eliminate HPV from their body. But if the person doesn’t have a healthy immune system, HPV may remain indefinitely.

Doctors can prescribe and administer treatments to strengthen the immune system and reduce HPV symptoms. But the best way to protect yourself from HPV and the risk of getting HPV-based cancer or genital warts is to get the HPV vaccine before an infection occurs.

How quickly can the immune system suppress HPV?

About 90% of HPV-infected women have immune systems that suppress the virus within two years after the initial infection. Sometimes the virus goes away in as little as six months.

A small percentage of HPV-infected women carry the virus beyond the two-year mark. As a result, it puts them at a higher risk of developing cervical cancer.

Do HPV infections come back again? 

When the immune system clears HPV from any further activity in the body, you won’t always know whether the virus has been eradicated completely or merely in a state of indefinite dormancy.

But even if the virus has been eradicated successfully, that is only one HPV strain. You could still become infected with a different HPV strain. Then your immune system must build antibodies to eliminate it again. 

What is the most effective supplement for treating an HPV infection?

AHCC supplements are the most effective because they contain vital nutrients to strengthen the immune system and fight HPV. These nutrients include amino acids, oligosaccharides, and various liquid culture-based minerals.

What is AHCC? 

AHCC is a patented compound derived from cultured shiitake mushroom extract with antioxidant properties.  Only one company in the world makes AHCC and that’s Amino Up Co., Ltd JAPAN. Look for the AHCC® trademark on the label.

Does consuming AHCC cause the immune system to generate more T cells?

Several studies including one from Yale School of Medicine studies show that AHCC consumption can double the number of T cells generated and their effectiveness.

What are the other benefits of AHCC?

In addition to fighting HPV infections, AHCC can support the immune system in treating cancer, prevent cancer, prevent microbial infections, and potentially avert oxidative stress-induced disorders. These benefits are due to the anticancer and anti-inflammatory properties contained in AHCC.

What is the most recommended AHCC supplement for treating HPV infections?

Look for products containing genuine AHCC with little to no fillers. Also, ensure it is authentic AHCC because many online supplement companies sell generic products with no benefits.  The best advice is to shop for AHCC supplements from a reputable brand that has excellent reviews and has been established with a history of customer satisfaction and support.

When can I expect to see results after I start taking AHCC?

Most people notice results in as little as a month after they start taking AHCC consistently. However, you should take AHCC for up to six months to feel the full effects. Six months is usually the maximum time needed to treat HPV.

When is the best time to take AHCC?

Morning is the best time because you have an empty stomach. It is always better to consume AHCC when it has been at least a few hours since you last ate.  

Takeaway Advice

If you are having immune related issues or have been diagnosed with HPV or just want to optimize your health and well-being, talk with your healthcare provider.  Follow their advice on the best way to build your immune system and ask them if you should start adding AHCC to your health routine.